Seen this issue recently in the lab whereby any citrix published apps/desktops i looked to launch i could see took around 30 seconds to start launching. Other activities like “refresh apps” took similar lengths of time.
There was a workaround i invoked that was well reported on the web to verify in IE under
Internet Options > Connections > Lan Settings and untick “Automatically detect settings” tick box and Ok.
Did log a ticket with citrix regards this and they have released a private hotfix. If you have an enterprise environment and have the above setting ticked might need to go private hotfix route ask to test private hotfix version 14.4.1001.1. Has worked fine for me testing with it last week or so.